N-[(tert-Butoxy)carbonyl]-D-homoserine monosodium salt - Names and Identifiers
N-[(tert-Butoxy)carbonyl]-D-homoserine monosodium salt - Physico-chemical Properties
Molecular Formula | C9H17NO5
|
Molar Mass | 219.235 |
N-[(tert-Butoxy)carbonyl]-D-homoserine monosodium salt - Introduction
Sodium Boc-D-homoserine (N-[(Tert-Butoxy)Carbonyl]-D-Homoserine Monosodium Salt) is a compound mainly used in the field of organic synthesis.
Nature:
-Chemical formula: C11H19NNaO6S
-Molecular weight: 323.32g/mol
-Appearance: White crystalline powder
-Solubility: Soluble in water and some organic solvents
-Melting point: about 125-130 ℃
Use:
Sodium Boc-D-homoserine is commonly used as a protecting group for D-homoserine, protecting and temporarily modifying amino acids in organic synthesis. It can prepare biologically active molecules such as polypeptides and proteins by atomic economic synthesis methods.
Preparation Method:
The preparation of sodium Boc-D-homoserine is usually carried out by the following steps:
1. Reaction of D-homoserine with tert-butoxycarbonyl chlorocarbonate (tert-Boc-OSu) to give Boc-D-homoserine.
2. Boc-D-homoserine is reacted with a base, such as sodium carbonate (Na2CO3), to produce the sodium salt form of Boc-D-homoserine (sodium Boc-D-homoserine).
Safety Information:
Sodium Boc-D-homoserine is generally a stable and relatively safe compound under conventional conditions, but the following aspects still need to be paid attention:
-Wear appropriate protective equipment such as lab gloves, goggles and lab coats.
-Avoid direct contact with skin and inhalation of dust.
-Storage should be sealed, avoid humidity and high temperature environment.
-Follow laboratory safety practices and appropriate waste disposal methods when using.
The above information is for reference only. The specific experimental conditions and safe operation need to be evaluated and controlled according to the specific situation.
Last Update:2024-04-10 22:29:15